2600xt and 4670 on Vista x86, Vista x64 and Windows 7 fully working. Onboard Sound is working. But as usual, another soundcard (in my case it is an external Usb M-Audio piece o.s.) needs to be connected, but does not need to be the primary device. OpenGl? ... OpenGl Acceleration in Avid?! ^^ How did you get this to work?